Not for use in humans. Keep out of reach of children. In case of accidental injection or exposure seek medical advice. Topical exposure may elicit localized allergic skin reactions in some individuals. Repeated or prolonged exposure may lead to skin sensitization. In case of accidental skin exposure wash with soap and water. CERENIA is also an ocular irritant. In case of accidental eye exposure flush with water for 15 minutes and seek medical attention.
In puppies younger than 11 weeks of age histological evidence of bone marrow hypoplasia was seen at higher frequency and greater severity in puppies treated with CERENIA than in control puppies. In puppies 16 weeks and older bone marrow hypoplasia was not seen (See Animal Safety Section).
For subcutaneous injection only. The safe use of CERENIA has not been evaluated in dogs used for breeding pregnant or lactating bitches dogs with gastrointestinal obstruction or dogs that have ingested toxins. Use with caution in dogs with hepatic dysfunction. Use with caution with other medications that are highly protein bound. The concomitant use of CERENIA with other protein bound drugs has not been studied in dogs. Commonly used protein bound drugs include NSAIDs cardiac anticonvulsant and behavioral medications. The influence of concomitant drugs that may inhibit metabolism of CERENIA has not been evaluated. Drug compatibility should be monitored in patients requiring adjunctive therapy.
For subcutaneous injection in dogs only