There are no known contraindications for the use of Panacur® (fenbendazole) Paste 10% in horses.
Side effects associated with Panacur® (fenbendazole) Paste 10% could not be established in well-controlled safety studies in horses with single doses as high as 454 mg/lb (1000 mg/kg) and 15 consecutive daily doses of 22.7 mg/lb (50 mg/kg). Particularly with higher doses, the lethal action of fenbendazole may cause the release of antigens by the dying parasites. This phenomenon may result in either a local or systemic hypersensitive reaction. As with any drug, these reactions should be treated symptomatically.
Panacur® (fenbendazole) Paste 10% has been evaluated for safety in pregnant mares during all stages of gestation with doses as high as 11.4 mg/lb (25 mg/kg) and in stallions with doses as high as 11.4 mg/lb (25 mg/kg). No adverse effects on reproductivity were detected. The recommended dose for control of fourth stage larvae of Strongylus vulgaris, 4.6 mg/lb (10 mg/kg) daily for 5 consecutive days, has not been evaluated for safety in stallions or pregnant mares.
Internal Parasites: Regular deworming at intervals of six to eight weeks may be required due to the possibility of reinfection. Migrating Tissue Parasites: In the case of fourth stage larvae of Strongylus vulgaris, treatment and retreatment should be based on the life cycle and epidemiology. Treatment should be initiated in the spring and repeated in the fall after a six-month interval.
Optimum Deworming Program for Control of S. vulgaris: Optimum reduction of S. vulgaris infections is achieved by reducing the infectivity of the pastures. When horses are running on pasture, in temperate North America, maximum pasture infectivity occurs in October-December. If horses are removed from those pastures in January, pasture infectivity will decline to zero by July 1. Egg production of S. vulgaris is minimal from January through April, peaking in August and declining to minimal values in December.
Recommended Deworming Program:** December 1, February 1, April 1, June 1, August 1, October 1.
The two treatments that are in bold type are the recommended periods when the 5-day treatment regimen for the control of the migrating larvae of S. vulgaris should be performed.
** For other areas in the world, retreatment periods for the migrating larvae of S. vulgaris may be different; consult with your veterinarian.
Keep this and all medications out of the reach of children.
When using Panacur® (fenbendazole) Paste 10% concomitantly with trichlorfon, refer to the manufacturer's labels for use and cautions for trichlorfon.
Do not use in horses intended for food.