ToxiBan is the "gold standard" for treating animal poisonings.
Toxicants That Bind to MedChar™,
Activated Charcoal, USP |
Acetaminophen
Amphetamines
Anthelmintics
Antibiotics
Aspirin
Atropine
Barbiturates
Camphor
Cantharides
Carbamazepine
Carbamates
Chlordane
Chloroquine
Chlorpheniramine
Cocaine |
Diazepam
2,4-D (dichlorophenoxy
acetic acid)
Digitalis
Digitoxin
Ethylene glycol*
Fungicides
Hexachlorophene
Ipecac
Isoniazid
Malathion
Mefenamic acid
Meprobamate
Methylene blue |
Methyl salicylate
Morphine
Muscarine
Narcotics
Nicotine
Nortriptyline
Organic iodine
Organic metal compounds
Organochlorine insecticides
Organophosphorus
insecticides
Parathion
Phenobarbitol
Phenothiazine |
Phenylbutazone
Phenylpropanolamine
hydrochloride
Phenytoin
Quinacrine hydrochloride
Quinidine
Quinine
Rodenticides
Salicylamide
Salicylates
Strychnine
Sulfonamides
Theophylline
Tricyclic antidepressants |
| *Tests for ethylene glycol must be conducted before ToxiBan
is administered to prevent false positive reactions. |
Indications and Usage:
ToxiBan® is most effective when administered as soon as
ingestion of a toxicant is suspected. It may be used in some
emergencies when absorption of the toxicant is nearly complete
or the exposure was via a parenteral route. This latter
application usually involves repetitive or multiple doses.
Multiple doses may be used to interrupt the enterohepatic circulation
of some toxins, thereby preventing their reabsorption.
See package insert for more detailed information.
Contraindications:
There are no known absolute contraindications to the use of
activated charcoal. It should not be given simultaneously or
shortly before the oral administration of other therapeutic agents
such as antibiotics, vitamins or amino acids. Antibiotic therapy
should be administered parenterally when ToxiBan is used.
Dosage:
Suspension and Suspension w/Sorbitol
For small animals, use 10 to 20 mL per kg (5 to 10 mL per
pound) body weight. For large animals, use 4 to 12 mL per
kg (2 to 6 mL per pound) body weight.
Granules:
To make a thin suspension, mix 1 volume measure with 5 to
7 parts cold water (Example: 1 level cup ToxiBan to 6 cups
water). Agitate vigorously for 10 to 30 seconds. For small
animals, use 2 to 4 grams per kg (1 to 2 grams per pound)
body weight. For large animals, use 0.75 to 2.0 grams per
kilogram (0.35 to 0.9 grams per pound). One pound
(453.6 grams) normally treats an animal weighing 225 to
600 kilograms (500 to 1300 pounds).
Administration:
ToxiBan Suspension and Suspension with Sorbitol may be
given directly or mixed with a small amount of cold water to
reduce viscosity. For Granule administration, use as a powder
in food or dilute to create a suspension. When a suspension is
created, agitate frequently to keep liquid uniform. A stomach
tube is preferred, but an oral drench may be used in emergency.
Precautions:
ToxiBan is an adjunct in the management of poisoning
emergencies. Prior to use, proper life support and gastric emptying
must be implemented, if indicated. Because more than an
hour may pass before ToxiBan can be administered without
regurgitation after an emetic has been given, it may be more
effective to give ToxiBan immediately because adsorption of a
toxicant may be a more effective removal than vomiting.
ToxiBan produces black stools. These stools may have a
diarrhea consistency and may persist for several hours.
Sorbitol can create a profound cathartic effect. Proper
attention should be provided to fluid and electrolyte needs to
prevent dehydration, possible hypernatremia and even
hypotension. ToxiBan Suspension should be used for multiple
use, and cathartics should only be used intermittently during
multiple dose activated charcoal use.
Ingredients:
MedChar (activated charcoal, USP), Kaolin, and Sorbitol (in
granules and suspension with sorbitol). Granules contain
wetting and dispersing agents.
MedChar (a medicinal grade of activated charcoal), contained in all three products, is a small particle size type of vegetable charcoal that possesses a relatively high activity as an adsorbent of organic chemicals. It has been processed by Vet-A-Mix to enhance its adsorptive power and reduce dustiness. Its adsorptive activity exceeds the USP standard for activated charcoal. |