Amplimune is a one-time immunotherapeutic treatment for calves 1 to 5 days old. Amplimune is used to reduce mortality and clinical signs associated with calf scours caused by E. coli K99. Administer 1 ml intravenously. Dosage: Aseptically administer 1 ml intravenously. 21 day slaughter withdrawal.Early administration in the disease process stimulates non-antigen related defense mechanisms and enhances calf's innate immune defense system to minimize and control damage caused by pathogenic E. coli.Anaphylactoid reactions may occur. Antidote: Epinephrine.U.S. Lic. No. 289.