EXCEDE® (ceftiofur crystalline free acid) Sterile Suspension is the first and only FDA-approved antibiotic for horses that offers a full course of therapy in just two doses. EXCEDE reduces the treatment requirements from 10 once-or twice-daily doses of an oral antibiotic, such as trimethoprim-sulfonamide (TMS), to just two doses. This can make treating equine respiratory infections less stressful for the horse and more convenient for the veterinarian and the horse owner.